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AOD 9604 had no effect on serum IGF-1 levels at any dose tested

The peptide, typically administered as a nasal spray, has shown the most promise in humans for treating neurological conditions, particularly ischemic stroke, but there is no evidence for general cognitive enhancement

33176370 Der-Nigoghossian C, Tesoro EP, Strein M, Brophy GM

In human beings, the maintenance of reduced body weight is achieved via coordination of metabolic, neuroendocrine, and autonomic responses that normally favor weight regain following a loss [40]

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Molecular endocrinology 28 , 860871, doi:10.1210/me.2014-1038 (2014)