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Studies of decompensated cirrhosis and ACLF consistently show that patients with intense systemic inflammation can improve dramatically if the precipitating event is controlled but have high competing mortality risk (Saeidinejad et al., 2023)

Folic Acid Supplementation Attenuates Chronic Hepatic Inflammation in high-fat diet fed mice

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N Engl J Med 1999;341:1670-9