Early treatment efficacy of S-adenosylmethionine in patients with intrahepatic cholestasis: a systematic review
Birth Defects Res 109(5):336346 Deayton JR, Sabin CA, Johnson MA, Emery VC, Wilson P, Griffiths PD (2004) Importance of cytomegalovirus viraemia in risk of disease progression and death in HIV-infected patients receiving highly active antiretroviral therapy
The positive correlations in human CSF of Xan and several monoamines including 5-HIAA have been noted earlier ( PURINERGIC SIGNALING, CLINICAL IMPROVEMENT, AND NEUROLOGICAL DEFICITS Associations between purine metabolites and clinical and neurological symptoms were examined before and after 4w antipsychotic treatment ( greater improvement in clinical functioning 1 month later ( Figure 4 )
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Downregulation of SLC7A11 disrupts cysteine metabolism, leading to decreased intracellular cystine and GSH levels, impairing GPX4 activity and triggering lipid peroxide accumulation and ferroptosis (79,81,82)