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Another trial that enrolled patients with type 2 diabetes showed an average weight loss of nearly 6% from baseline and a difference of approximately 4% compared to treatment with placebo at one year

Healthy mitochondrial function may support glutathione recycling* NAD+ is essential for mitochondrial efficiency

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And that I think what explains that is just the vicious cycle of the mitochondria got, they lost a quarter percent here or a quarter percent there, and they just started repairing themselves less effectively because theyre the engines fueling everything, including that