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In CNS- Glud1 +/ /Stress mice, stress may limit the ability of the mPFC to regulate glutamate homeostasis [64, 65], and hinder the competency of the mPFC to implement compensatory mechanisms critical for intact homeostasis at the glutamate tripartite and glutamate-GABA synapses
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Individuals with glutathione synthetase deficiency or on acetaminophen therapy should consult a provider before supplementation
Impact of streptozotocin on altering normal glucose homeostasis during insulin testing in diabetic rats compared to normoglycemic rats
Similarly, green tea extract (which carries rare but serious liver injury risk at high doses) and cinnamon (particularly cassia cinnamon, which contains coumarin) have been studied for metabolic effects, but there is no robust evidence they meaningfully enhance incretin hormone activity in humans
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