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The mechanisms AHK-Cu targets VEGF-driven angiogenesis, TGF-1 inhibition, collagen reinforcement are relevant to both male and female androgenetic alopecia

Naltrexone-bupropion is described as an opioid antagonist paired with dopamine and norepinephrine reuptake inhibition, while off-label metformin is framed as working through insulin sensitivity and gut glucose absorption

This comprehensive approach aims to improve weight loss outcomes, addressing the needs of the estimated 12 million individuals in the UK who qualify for GLP-1 treatments

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Smoking cessation is also beneficial, provided that it does not result in body weight increase [129]