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MiR-182 suppresses CUL5 translation or promotes its degradation, leading to abnormal accumulation of downstream JAK2 and Fas-L, which drives tumor cell proliferation (13)

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Briefly, under visualization with an operating microscope, 50 L of any one of the formulations described herein is injected using a 25 G (Gauge) 1 inch needle through the tympanic membrane into the superior posterior quadrant

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