NNMT is expressed in some cancer cells, which makes interpretation of inhibition complex: effects could differ by cancer type or stage, and the data are largely from models rather than long-term human study
Monitoring: Regular colonoscopies, blood tests, and imaging are important for monitoring disease activity, medication safety, and cancer surveillance (long-standing Crohns colitis increases colorectal cancer risk)
Not suitable for pregnant or breastfeeding women unless advised by a healthcare professional
References and Further Reading Sikiric P, et al
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doi: 10.1101/cshperspect.a029025 257 Baecher-AllanCKaskowBJWeinerHL