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Additionally, metformin administration significantly increased SOD activity in MIA-induced OA mice, no significant change was observed in GSH-PX levels (Fig

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Acute injury or inflammation

It is currently believed that the protein level of SLC25A39 is regulated by a dual mechanism involving the mitochondrial protease ATPase family gene 3-like 2 (AFG3L2) and iron sensing [22, 23]

Side effects occur in less than 5% of treatments and are typically mild, temporary, and easily managed with proper screening and monitoring protocols