The Dose-Response Question: Yes, higher doses produce more dramatic effects
The study authors note that this effect size is similar to what is observed with many approved drug therapies, minus the side effects and costs
The PlexusDx Microdose GLP-1 Protocol is $129/mo flat ($1,548/year), below SHEDs lowest compounded tier
What the Research Suggests About Weight Regain Clinical research supports the idea that ongoing management matters
Several mechanisms might explain possible benefits: Improved glycaemic control : Better blood glucose regulation may reduce endothelial dysfunction and microvascular damage, both implicated in ED pathophysiology Weight reduction : Significant weight loss can improve testosterone levels, reduce inflammation, and enhance vascular function Cardiovascular effects : GLP-1 agents may improve endothelial function and reduce cardiovascular risk factors that contribute to ED Reduced inflammation : These medications have been associated with anti-inflammatory effects that might benefit vascular health, though more research is needed Some observational studies have reported improvements in erectile function scores among men with diabetes treated with GLP-1 receptor agonists, though the evidence is limited and more robust research is needed

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