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The number of patients requiring rescue antihistamines was 26% lower in the Pycnogenol group than in the placebo group

29,30 Overlapping days supply from early refills was accounted for and continued medication use was assumed during hospitalizations

FDA.gov Regulatory Guidance .

However, like every drug, it has to be consulted with a health care provider to ascertain whether it can be appropriately prescribed to such an individual based on their individual health needs and lifestyle.

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