B12 Deficiency Symptoms and Risk Factors B12 deficiency is more common than most people realise and is frequently missed or misattributed to other causes
This statement is supported by the large decrease in GSH of more than 50% in both nuclei and cytosol of Cd-exposed trichome cells [59,158,166,173]
The other one has the full on disease 40 years later, but its the same exact pathology, the same pathways just delayed 30, 40 years

20 min LH, due to hyperglycosylation) Mechanisms of Action: LH/hCG Receptor Activation (LHCGR): Receptor: GPCR (7-transmembrane) in testicular Leydig cells, ovarian theca Translation: Gs protein coupling adenylate cyclase cAMP PKA Cascade: StAR (steroidogenic acute regulatory protein) phosphorylation Result: Mitochondrial cholesterol transport steroidogenesis Testicular Steroidogenesis: Leydig cells: testosterone synthesis stimulation Key enzymes: CYP11A1 (side-chain cleavage), 3-HSD, 17-HSD Testosterone production: 200400% increase in baseline levels Paracrine effects: spermatogenesis support (Sertoli cells) Ovarian Function Preovulatory follicle: final maturation, ovulation Corpus luteum: maintenance of progesterone production Luteinization: granulosa/theca cell differentiation Angiogenesis: luteal body vascularization (VEGF pathway) Recombinant hCG Pharmacokinetics: SC bioavailability: 4050% (vs

(17), we conducted a literature search of newer articles (2014 present), and after filtering out reviews, identified 17 additional English language studies assessing APA and various semen analysis parameters (6, 8, 9, 1831) (Table 1)
B12 gets the process working again