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Phenolic and catecholic compounds are chemical structures found in some industrial and cosmetic agents that may be toxic to melanocytes in susceptible people

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Abbreviations: DLT, dose-limiting toxicity

1 Introduction Hypertension (HTN) and diabetes mellitus (DM) are interconnected metabolic disorders driving global cardiovascular morbidity, with oxidative stress (OS) implicated as a key pathological link (Myszko et al., 2025)

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