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Because of lack of sensitivity and problems with non-specificity of commercially available GLP-1R antisera detected multiple nonspecific immunoreactive proteins even in tissue extracts from Glp1r -/- mice

It can also manifest as subclinical hypothyroidism, a more subtle form that isnt always easy to diagnose

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Current areas of scientific investigation include extracellular matrix signaling analysis, peptide-metal coordination studies, redox-sensitive signaling pathway research, transcription-associated metal regulation, copper-mediated cellular signaling investigations, and matrix-associated biochemical pathway analysis