glp-1 and type 2 diabetes GLP-1-based therapies for diabetes: from single, dual triple agonists to endogenous production and L-cell differentiation | Diabetology & Metabolic Syndrome GLP-1: Actions on Beta-cell Mass

Tirzepatide is a dual agonist targeting both GLP-1 and GIP receptors, improving insulin sensitivity and promoting fullness, leading to superior weight losssome patients lose over 20%, with an average of 15%

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Relationships between gastric emptying, postprandial glycemia, and incretin hormones

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In a polymicrobial model of sepsis induced by cecal ligation and puncture, a GLP-1 analog ameliorated vascular inflammation and oxidative stress by improving endothelial function ( In a cardiac fibrosis model, the GLP-1 analogue liraglutide reduced vascular reactivity, cardiac hypertrophy, fibroblast accumulation, collagen deposition and MCP-1 production ( GLP-1 improved left ventricular function in patients with chronic heart failure and in dogs with dilated cardiomyopathy