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Its primary function is to potentiate insulin secretion in a glucose-dependent manner it only triggers insulin release when blood sugar is elevated, which explains why GLP-1 receptor agonists carry a low intrinsic risk of hypoglycemia

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, Semaglutide Versus Placebo in Patients With Heart Failure and Mildly Reduced or Preserved Ejection Fraction: A Pooled Analysis of the SELECT, FLOW, STEP-HFpEF, and STEP-HFpEF DM Randomised Trials, Lancet 404, no

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