A 2023 study found that patients with cardiovascular disease who were taking semaglutide, the active ingredient in Ozempic and Wegovy, had fewer cardiovascular-related deaths and fewer heart attacks
GLP-1 agonists reduce albuminuria (protein in the urine, a marker of kidney damage) and appear to slow the progression of diabetic kidney disease
The combined effects of these mechanisms of action make GLP-1 an effective treatment for type 2 diabetes and obesity, with ongoing studies exploring its broader therapeutic potential
This triple mechanism is what makes it potentially more effective for weight loss, and what drives much of the interest in retatrutide among people already using GLP-1 medications
Popular GLP-1 medications include semaglutide (Ozempic for diabetes, Wegovy for weight loss) and dulaglutide (Trulicity)
The MWM test was used to assess spatial (hippocampus-dependent) learning and memory