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574 Targeting the PPI network Protein-protein interactions (PPIs) are fundamental in maintaining cellular functions, while aberrant interactions between proteins are implicated in the pathogenesis of numerous diseases

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Its application has been studied extensively in clinical settings, especially for those dealing with obesity or insulin resistance

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In anesthetized rats, administration of Ang-(17) increased urinary flow rate and sodium excretion, an effect abolished by the Ang-(17) receptor antagonist A-779 (ref

Differential incretin effects of GIP and GLP-1 on gastric emptying, appetite, and insulin-glucose homeostasis