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doi: 10.1016/j.ejmech.2018.08.062

Bone Health: There is an associated risk of increased bone fractures in the hip, wrist, or spine with high-dose or long-term use

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Drug Interactions This medication may interact with: Other antihypertensive drugs Calcium channel blockers Certain heart rhythm medications NSAIDs (e.g., ibuprofen) Antiarrhythmics Always inform your healthcare provider about all medicines and supplements you are taking

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This hormone signals your brain that you are full, slowing down how quickly your stomach empties food, and reducing your appetite for both meals and snacks