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AOD9604 is not FDAapproved for any medical indication, and FDA advisory documents note concerns about immunogenicity, peptide-related impurities, and lack of sufficient safety and efficacy data

It was hypothesized that the lack of activity was due to the increased hydrophilicity provided by the sulfur-containing bridging unit when compared to the control analog used, lipobactin, in which the lipid is attached directly to the N -terminus

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doi: 10.1016/S0140-6736(11)61452-9 124

Glutathione is composed of three amino acids (L-glutamic acid, L-cysteine and glycine) and can be found in every cell