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It was not until the development of an in-vitro carnitine uptake assay on cultured fibroblast, a clear-cut definitive diagnosis of CUD could be made.2 However, in-vitro functional assay has many limitations and the most obvious one is the unavailability of living fibroblast as fibroblast culture from skin biopsy is not a routine investigation that is readily available

doi: 10.1038/s43587-024-00795-w 232 ZhangY.YangW

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Generally, the hair will begin to shed two to three months after beginning the medication or upping your dose, so its important to keep an eye out for the signs

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