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Conflict of interest Warren Ladiges is a member of the Editorial Board of Aging Pathobiology and Therapeutics
Hesperidin (HES) Hesperidin (HES) is a bioflavonoid with antioxidant effects that are widespread in citrus fruits [131, 132]
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INCI name- Glutathione
Elevated serum copper levels, often observed in aging and diabetes, are both a driver and a biomarker of vascular damage, forming a vicious cycle that accelerates vascular aging and increases the risk of cardiovascular disease [40, 41]
Isopentenylation The post-transcriptional modification of base 37 in tRNA with isopentenyl leading to the formation of N 6 -isopentenyl adenosine (i6A)
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