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Another was the discovery that tight junctional permeability is dynamic, altered by systemic inflammation and other factors such as enterotoxins and the volume of fluid absorption [23, 39], initially reported in the early 1980s in clinical studies of intestinal permeability in arthritis and celiac disease patients [37, 40]

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Emerging delivery technologies, such as nanoparticles, liposomes, microneedles, and intranasal systems, are being studied to improve peptide stability and absorption without injections

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The presence of free metals and complexes of A with metals act as catalysts for ROS production, ultimately leading to neuronal cell death

[DOI] [Google Scholar] 79.Kammoun M., Miladi S., Ali Y.B., Damak M., Gargouri Y., Bezzine S