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The better effect of LCLN than LC was evidenced by the findings of earlier studies 92,100 , likely due to physical attributes (including shape, size, and zeta potential), alongside enhancements in encapsulation efficiency, drug content, drug loading capacity, drug release, and in vitro release of the formulated LC-SLNs, all of which were optimized in the niosomal form 19

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Intravesical treatment Dimethyl sulfoxide It is a water-soluble and anti-inflammatory chemical solvent that is delivered directly to the bladder by a catheter