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Li, Z.H

When other receptor antagonists are administered, a compensatory increase in the circulating hormone levels is seen (115)

2009 Jul-Aug;23(4):567-75

suggests that a key element in this process involves the activation of G-proteins, which are closely associated with the inner surface of the cell membrane and activate downstream pathways leading to the production of secondary messengers such as cyclic adenosine monophosphate (cAMP) and inositol triphosphate (IP3)

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The biological rebound happens because your body perceives the sudden absence of GLP-1 as a caloric deficit that must be corrected