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Unusual hormonal status can lead to the inability of ovaries to release functional and mature follicles

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Assessment of paw swelling and clinical score The CIA mice were administered 100 L of PBS, MCMs, SP@M (4 10 7 cells/mL), SP (4 10 7 cells/mL), and MTX (5 mg/kg) intravenously every three days for a total of 10 times

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Apply light pressure with gauze or a clean cotton pad if any bleeding occurs