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Gut flora-dependent metabolite Trimethylamine-N-oxide accelerates endothelial cell senescence and vascular aging through oxidative stress

Endocrine and Thermoregulation Support Some research suggests DSIP has regulatory effects on body temperature, luteinizing hormone (LH), and melatonin secretion , possibly contributing to its role in sleep and recovery

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[DOI] [PubMed] [Google Scholar] 30.Derkacz R, Marciniak W, Baszuk P, Wysokinska M, Chrzanowska N, Lener M, et al

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Nevertheless, it is unclear how inhibition of GCL activity activates TOR signaling