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In several RCTs, GLP-1RAs, when used alone or in combination with other hypoglycemic agents including metformin, sulfonylurea, DPP-4 inhibitor, thiazolidinedione, and sodium-glucose cotransporter 2 inhibitor, showed superior or non-inferior blood glucose lowering ability compared to insulin treatment [64,65]

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Because of its dietary sources, vegetarians and vegans are at a higher risk of developing a deficiency

Niacinamide (B) in high pharmacological doses has less pregnancy data