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Vitamin B12 deficiency is relatively common, especially when on a restricted diet

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B vitamins play crucial roles in energy metabolism by aiding in the conversion of carbohydrates, fats, and proteins into usable energy for the body

Both were removed from FDA 503A Category 2 on April 22, 2026, but neither is on Category 1 either

Additionally, interactions with concurrent medications (lipid-lowering agents, diabetes medications, stimulants) have not been systematically evaluated