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10,11 These tangles impair synaptic transmission between neurons by interfering with the transport system inside the neuron

Plant Physiol 117:11031114 Vauclare P, Kopriva S, Fell D, Sutter M, Sticher L, von Ballmoos P, Krhenbhl U, Op den Camp R, Brunold C (2002) Flux control of sulphate assimilation in Arabidopsis thaliana: adenosine 5-phosphosulphate reductase is more susceptible that ATP sulphurylase to negative control by thiols

In-vitro experiments with glial cells, oligodendrocytes, brain explants, and adult stem cells have revealed that IGF-1 promotes myelination, differentiation and mitogenesis [31]

However, caution is still advised

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