Mechanism two (homocysteine NMDA excitotoxicity) : low mood, vascular dementia, memory issues, nervous system disease, stroke risk, and multiple sclerosis
Some might say this title is dramatic, but those who are currently denied access to B12 injections, who are panicked to within an inch of their lives with coronavirus and who now have no essential vitamin B12 treatment, would probably feel its a completely reasonable statement
Seedorf H, Fricke WF, Veith B, Brggemann H, Liesegang H, Strittmatter A, et al
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Turkish J Phys Med Rehabil
Morphine has a bioavailability of about 30% because 70% is metabolized via 1st pass effect (metabolism by the liver) if taken orally