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doi: 10.1152/ajpendo.00113.2017 [DOI] [PMC free article] [PubMed] [Google Scholar] 16

Description Retatrutide is a next-generation triple agonist peptide that acts on the GLP-1, GIP, and glucagon receptors

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Furthermore, the expansion of pathobionts like Peptostreptococcus can generate detrimental metabolites (e.g., indole derivatives), which directly upregulate cartilage-degrading MMP-13 (2628)

Intrinsic resistance stems from the inherent biological characteristics of a bacterial species and is present before any exposure to drugs

The primary antibodies used were anti--catenin (dilution ratio 1:5,000, Proteintech, Wuhan, China, Cat