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Appetite Regulation: By acting on GLP-1 receptors in the hypothalamus and other brain regions associated with appetite control, semaglutide reduces food intake and promotes satiety

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The theory proposes that some individuals may have difficulty breaking down lectins, leading to impaired digestion, nutrient absorption, gastrointestinal inflammation, disruption of the gut microbiome, and potentially contributing to leaky gut and systemic inflammation, which could trigger autoimmune issues

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The most compelling research endpoints involve mortality and disease incidence tracked over years, as demonstrated in the long-term follow-up studies showing reduced mortality in treated groups