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One difference between their model and the one reported here is that deletion of Gclc is induced in hepatocytes of adult mice (which are slowly proliferating), compared to theirs, where deletion of Gclc occurred in hepatocytes of growing animals (which are rapidly proliferating)

The P53 family orchestrates the regulation of metabolism: physiological regulation and implications for cancer therapy

Three levels of hazard controls are: 1

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While microdosing protocols have not yet been subject to equivalent large-scale clinical trials, preliminary observations suggest promising applications in specific patient populations

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