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GHK-Cu is used as a cosmetic ingredient (copper tripeptide-1) in topical skincare, where ingredients are regulated differently from drugs

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Along with preclinical data indicating that long-acting GIPR agonists act in the brain to decrease body weight and food intake via GIPR signalling in inhibitory -aminobutyric acid-producing (GABAergic) neurons 5,6,7 , and by mitigating the emetic effects of GLP-1R agonism 8,9 , GIPRGLP-1R co-agonism has been established as a highly effective strategy for the management of obesity, type 2 diabetes and MASH

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The presence of comorbidities As we know, obesity is related to and a risk factor for a number of other cardiometabolic conditions, which means that many of my patients have multiple conditions that I need to be aware of and manage