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Zhang S, Wang J, Liu L, Sun X, Zhou Y, Chen S, et al

In murine studies, deletion of the IGF-1R in skeletal muscle resulted in glucose intolerance issues ultimately leading to T2D at an early age, because, although they express insulin receptors, they cannot form hybrid or IGF-1 receptors [162]

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However long term safety and potential risks are still being investigated and these compounds are for research use only

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