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During the meeting, several members questioned whether FDA placed too much emphasis on the lack of randomized clinical trials and too little weight on clinical experience and other available evidence, while members opposing the recommendations argued the committee should rely on stronger scientific evidence rather than growing consumer demand

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However, not every medication in this space works exactly the same way

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Such sex-specific effects suggest that the hormonal modulation of HPA axis activity plays a key role in shaping differential stress responses between males and females throughout the day, potentially leading to distinct daily patterns in HPA axis output and regulation

North America contributes the largest share to the market as the region has a structured ecosystem for adopting GLP-1 analogs