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The dose of NAC (200 mg/kg) used in our present study is similar to this clinical dose

Fetuin-A Fetuin-A is a multifunctional glycoprotein secreted by the liver, and has been shown to be an important inhibitor of mitral annular calcification in persons with CHD and without severe kidney disease 86 and valvular calcification in patients with end-stage renal disease

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Effects of treatment of impaired glucose tolerance or recently diagnosed type 2 diabetes with metformin alone or in combination with insulin glargine on beta-cell function: Comparison of responses in youth and adults