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If small particles remain, set the vial down for 5 minutes and swirl again

You want the procedure to be routine, not something you are figuring out for the first time in a dimly lit hotel bathroom

Mycologia 92(6):10331042 Tan SX, Greetham D, Raeth S, Grant CM, Dawes IW, Perrone GG (2010) The thioredoxin-thioredoxin reductase system can function in vivo as an alternative system to reduce oxidized glutathione in Saccharomyces cerevisiae

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Individuals who are pregnant, breastfeeding, or have a history of certain medical conditions, such as pancreatitis or medullary thyroid carcinoma, should not use it