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The glucagon receptor component is thought to contribute to increased energy expenditure, though this too is based largely on early clinical and preclinical observations rather than definitive human data

This variability limits direct comparisons but also highlights the robustness of the observed protective trends

doi: 10.2337/db16-1477 9 LarssonSCOrsiniNWolkA

Clinical characteristics of and risk factors for chronic kidney disease among adults and children: an analysis of the CURE-CKD registry

Available from: 13 Bloomberg interview with John Furner, US CEO of Walmart

The week between medications is brief enough that significant regain is unlikely