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The World Health Organization issued its first global guideline endorsing GLP-1 therapies (liraglutide, semaglutide, tirzepatide) for long-term obesity treatment in adults

However, while these medications are highly effective for shedding pounds, they can also accelerate aging effects on the skin

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7i-n, LPS-induced Raw 264.7 cells (PBS) displayed marked inflammatory characteristics compared to the control, including a notable increase in pro-inflammatory cytokines IL-1, IL-6, and TNF-, as well as abnormal activation of the NF-B signaling pathway

It combines well with metformin, SGLT-2 inhibitors, and insulin