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In the context of incretin peptides, the relevant receptors are the cell-surface proteins that respond to the natural gut hormones GLP-1 (glucagon-like peptide-1), GIP (glucose-dependent insulinotropic polypeptide), and glucagon

Conservative dose schedule for sensitive individuals Not everyone tolerates the standard 4-week escalation well

Switching between GLP-1 medications There are a few reasons why your clinician may suggest switching GLP-1s

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Cosmetic changes, including hair loss, muscle loss, loose or sagging skin, and more pronounced wrinkles

Patients should be monitored for depression, suicidal thoughts or behavior, and any unusual changes in mood or behavior