Fatigue accompanied by other concerning symptoms including: Persistent dizziness, lightheadedness, or fainting Rapid or irregular heartbeat Shortness of breath or chest pain Severe or unrelenting nausea and vomiting Inability to keep down food or fluids for more than 24 hours Dark urine, markedly reduced urination, or swelling (signs of dehydration or kidney problems) Yellowing of skin or eyes Severe abdominal pain Mood changes, depression, or difficulty concentrating Signs of potential complications require immediate attention: Stop the medication and seek urgent medical care if you experience severe abdominal pain (especially radiating to the back) which could suggest pancreatitis Stop the medication and seek urgent care if you develop symptoms of severe allergic reaction (rash, itching, swelling, severe dizziness, trouble breathing) Symptoms suggesting gallbladder disease (right upper abdominal pain, especially after eating) Hypoglycemia in patients taking diabetes medications (shakiness, sweating, confusion) Inability to meet nutritional needs despite best efforts, or unintentional weight loss exceeding recommended rates (generally more than 1-2 pounds per week after the initial period)
Ma L, Chen C, Zhao C, Li T, Ma L, Jiang J, et al
Over time, skin appears clearer, smoother, and more even
Use backup contraception methods like condoms for at least 4 weeks after starting Retatrutide and after each dose increase
Prolonged symptoms without treatment may lead to deconditioning and anxiety that complicate recovery
Can you provide documentation for regulatory submissions
