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Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro

It transports long-chain fatty acids into the mitochondria so they can be oxidized to produce energy

Finally, searching for biomarkers to predict the efficiency of glutamine targeting, or metabolomic and proteomic approaches to identify metabolic compensation mechanisms, will significantly improve the efficacy of cancer treatment

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162,163 The pharmacological basis of their action is increasingly being elucidated through both in vitro and in vivo experimental models, especially in conditions like IBS, peptic ulcers, GERD, and IBD, such as Crohns disease and ulcerative colitis