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The timing of exposure varied across the studies: two analyzed any exposure during pregnancy, whereas the other five focused on first-trimester exposure

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252 GLP-1 receptor agonists have emerged as an important treatment option for diabetic kidney disease in the context of type 2 diabetes, with semaglutide showing reduced risk of clinically important kidney outcomes and death from cardiovascular causes in people with type 2 diabetes and chronic kidney disease

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These results may explain why colorectal cancer tumors show higher levels of NAMPT than are shown by the normal paired samples