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D.et al (2015)

Studies showed that up to 40% of weight lost on semaglutide and tirzepatide was lean tissue, not fat

Soni D, Sagar P, Takkar B

Each step roughly doubles the previous dose rather than adding a fixed increment

Additionally, in obese humans, visceral fat deposits accumulate where the membrane composition regulating protein ATB8B1 (or flippase) is upregulated (Motahari-Rad et al., 2022)