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The differences of amino acid composition and electrostatic potentials on the oligomerization loop may affect the binding of large substrates to rhGPx3 mutant

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Interestingly, the decrease in staining intensity was more pronounced in the brains from female mice than male mice, even though the peptide showed a more effective increase in resilience to cognitive decline in males

Change history 18 September 2025 Following the article's publication, the Funding section was updated

Having said all of this, I still want to make the case for using metformin even if you decide you may need a stronger and better alternative

This level of weight loss is clinically meaningful and associated with improvements in metabolic health