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doi: 10.2174/092986706778773086

Low-dose aspirin is not routinely recommended for primary prevention in individuals without established disease, due to the risk of bleeding outweighing potential benefits in most cases

The agency has also warned that more serious risks can include pancreatitis or gallbladder problems

Importantly, while weight loss represents a major contributor to the clinical benefits of GLP-1RAs, accumulating evidence indicates that these agents also exert non-weight-dependent effects