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In the Standards of Medical Care in Diabetes2021, the ADA recommend that for people with indications of high risk or established CKD either a sodium-glucose co-transporter-2 inhibitor (SGLT2i) or a glucagon-like peptide-1 receptor agonist (GLP-1 RA) be considered as a treatment option, independently of metformin use [15]

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Relying solely on Semaglutide without incorporating healthy lifestyle changes may limit long-term success

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Researchers who understand the calculator fundamentals will be able to adapt to any protocol changes seamlessly, because the underlying math never changes

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