glp 1 with thyroid nodules and Increased screening may lead to higher cancer risk after GLP-1 initiation The Thyroid Twist: How GLP-1 – GLP-1 and Thyroid Cancer Link

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The serendipitous discovery of exendin-4 led to the development of exenatide immediate-release (exenatide IR, Byetta), a synthetic version of exendin-4 with C-terminal amidation to enhance its stability [ Figure 2 , Table 1 ], which became the first FDA-approved GLP-1RA in 2005 for the treatment of T2DM in adults [ Table 2 ]

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